...today’s research to satisfy the markets of tomorrow. The New Zealand Society of Animal Production has been the major NZ forum for the presentation of research results on farmed animals including: sheep, cattle, dairy, deer and goats for over 50 years. Over 500 farmers, farm advisors, veterinarians, scientists and university students are members of the Society.

BRIEF COMMUNICATION: Understanding the interaction of prolactin and leukaemia inhibitory factor signalling during the switch from lactation to involution

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K. SINGH, I. VETHARANIAM, M. PREWITZ, J. DOBSON and K. STELWAGEN

Proceedings of the New Zealand Society of Animal Production 69: 65-67

The molecular mechanisms involved in involution of the bovine udder, a process which underpins lactation persistency, are poorly understood. During rodent lactation, STAT5 is activated in response to prolactin (PRL) to stimulate milk protein production (Liu et al., 1997). At the onset of involution, STAT5 is rapidly inactivated (Schmitt-Ney et al., 1992), and STAT3 is activated by leukaemia inhibitory factor (LIF) to... Continued

Keywords: NZSAPAB; involution; cell signalling; mathematical modelling.

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Last Updated 14/07/2009

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Last modified: 11th November 2009