...today’s research to satisfy the markets of tomorrow. The New Zealand Society of Animal Production has been the major NZ forum for the presentation of research results on farmed animals including: sheep, cattle, dairy, deer and goats for over 50 years. Over 500 farmers, farm advisors, veterinarians, scientists and university students are members of the Society.

BRIEF COMMUNICATION: DNA methylation events associated with the suppression of milk protein gene expression during involution of the bovine mammary gland

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K. SINGH, K. SWANSON, C. COULDREY, H-M. SEYFERT and K. STELWAGEN

Proceedings of the New Zealand Society of Animal Production 69: 57-59

During lactation, prolactin activates STAT5 (Signal Transducer and Activator of Transcription), which binds to conserved DNA sequence motifs in promoters of milk protein genes to stimulate their expression (Liu et al., 1997). At drying-off, mammary involution is characterised by a rapid decrease in milk protein gene expression (Goodman & Schanbacher, 1991), including αS1-casein (Singh et al., 2008). The αS1-casein promoter features... Continued

Keywords: NZSAPAB; involution; epigenetics; bovine.

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Last Updated 14/07/2009

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Last modified: 11th November 2009